⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903520 | 0.72 | — | — | |
| SCHEMBL9461909 | 0.71 | — | — | |
| SCHEMBL10785369 | 0.69 | — | — | |
| SCHEMBL10403672 | 0.69 | — | — | |
| SCHEMBL4067490 | 0.67 | — | — | |
| SCHEMBL3812944 | 0.67 | — | — | |
| SCHEMBL6141164 | 0.67 | — | — | |
| SCHEMBL29053805 | 0.66 | CHRM2 (0.33) | — | |
| SCHEMBL5902453 | 0.65 | — | — | |
| SCHEMBL2086199 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4508413-B2 | — | — | 2010-07-21 | — | — | JP | claimed |
| US-20060270606-A1 | Dolastatin 15 derivatives | ABBOTT GMBH & CO., KG (DE) | 2006-11-30 | — | — | US | claimed |
| US-20030153505-A1 | Dolastatin 15 derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | US | claimed |
| US-6143721-A | FOR TREATING CANCER IN MAMMALS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | claimed |
| EP-0991658-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | claimed |
| WO-1999003879-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | claimed |
| EP-3189083-B2 | POLYCYCLIC PHOTOINITIATORS | IGM GROUP B V (NL) | 2023-07-05 | — | — | EP | disclosed |
| EP-3189083-B1 | POLYCYCLIC PHOTOINITIATORS | IGM GROUP B V (NL) | 2020-04-08 | — | — | EP | disclosed |
| US-10113075-B2 | Polycyclic photoinitiators | IGM MALTA LIMITED (MT) | 2018-10-30 | — | — | US | disclosed |
| US-20170240755-A1 | POLYCYCLIC PHOTOINITIATORS | IGM GROUP B.V. (NL) | 2017-08-24 | — | — | US | disclosed |
| EP-3189083-A1 | POLYCYCLIC PHOTOINITIATORS | IGM Malta Limited (MT) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016034963-A1 | POLYCYCLIC PHOTOINITIATORS | BASF SE (DE) | 2016-03-10 | — | — | WO | disclosed |
| US-20130046077-A1 | DOLASTATIN 15 DERIVATIVES | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2013-02-21 | — | — | US | disclosed |
| EP-0297496-B1 | Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KK (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5245052-A | PROCESS FOR PRODUCING 6-ACYL-7-DEACETYLFORSKOLIN DERIVATIVES | NIPPON KAYAKU CO. LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| CN-1016869-B | Process for preparing 6, 7-diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KK (JP) | 1992-06-03 | — | — | CN | disclosed |
| CN-1060291-A | The novel method of preparation 6-acyl group-7-deacetylforskolin derivatives | HOECHST JAPAN (JP) | 1992-04-15 | — | — | CN | disclosed |
| EP-0469428-A1 | Novel process for producing 6-acyl-7-deacetylforskolin derivatives | HOECHST JAPAN LIMITED (JP) | 1992-02-05 | — | — | EP | disclosed |
| CN-1030583-A | Preparation 6,7-diacyl-7-takes off the novel method of acetyl forskrine derivant | NIPPON KAYAKU KK (JP) | 1989-01-25 | — | — | CN | disclosed |
| EP-0297496-A2 | Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-01-04 | — | — | EP | disclosed |