Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2233153 | 0.90 | GAA (0.50) | MAPTHTTALDH1A1KDM4EHPGD | |
| SCHEMBL14058374 | 0.90 | PTK2 (0.47) | CSNK2A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2299923 | 0.81 | PTK2 (0.50) | MAPTHTTALDH1A1KDM4EHPGD | |
| SCHEMBL20895109 | 0.78 | EGFR (0.43) | EGFRLCK | |
| SCHEMBL2313044 | 0.77 | MAPT (0.45) | CSNK2A1MAPTALDH1A1BRAFABL1 | |
| SCHEMBL14137147 | 0.75 | MAPT (0.52) | MAPTHTTALDH1A1KDM4EHPGD | |
| SCHEMBL20895384 | 0.75 | CSNK2A1 (0.41) | CSNK2A1MAPTABL1BCR | |
| SCHEMBL2233664 | 0.75 | ABL1 (0.48) | CSNK2A1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL2233672 | 0.75 | ABL1 (0.48) | CSNK2A1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL14057141 | 0.74 | PTK2 (0.48) | CSNK2A1MAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141552-B1 | THIENOPYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE | HANMI PHARM IND CO LTD (KR) | 2019-04-17 | — | — | EP | claimed |