Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11908501 | 0.89 | FGFR3 (0.68) | KDRFGFR3 | |
| SCHEMBL11909507 | 0.87 | KDR (0.65) | KDRFGFR3 | |
| SCHEMBL11909474 | 0.87 | FGFR3 (0.66) | KDRFGFR3 | |
| SCHEMBL3322879 | 0.86 | FGFR3 (0.54) | KDRFGFR3 | |
| SCHEMBL3324434 | 0.86 | FGFR3 (0.52) | KDRFGFR3 | |
| SCHEMBL20895722 | 0.85 | KDR (0.66) | KDRFGFR3 | |
| SCHEMBL11907993 | 0.84 | FGFR3 (0.65) | KDRFGFR3 | |
| SCHEMBL11908369 | 0.84 | KDR (0.67) | KDRFGFR3 | |
| SCHEMBL11908090 | 0.84 | FGFR3 (0.68) | KDRFGFR3 | |
| SCHEMBL11909121 | 0.84 | FGFR3 (0.68) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300465-B1 | IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES | ASTEX THERAPEUTICS LTD (GB) | 2019-04-17 | — | — | EP | disclosed |