Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20981879 | 1.00 | CCNE1 (0.46) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL20895827 | 1.00 | CCNE1 (0.46) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL20981880 | 1.00 | CCNE1 (0.46) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL2359140 | 0.96 | CCNE1 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL21240851 | 0.96 | CCNE1 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL2359510 | 0.96 | CCNE1 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL21240852 | 0.96 | CCNE1 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL2358940 | 0.96 | CCNE1 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL2358529 | 0.96 | CCNE2 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 | |
| SCHEMBL2359766 | 0.96 | CCNE2 (0.49) | CCNE1CDK2CCNE2GBA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350078-B1 | COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS | NOVARTIS AG (CH) | 2019-04-17 | — | — | EP | disclosed |