Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20895847 | 1.00 | DPP4 (0.62) | DPP4CHRM1 | |
| SCHEMBL12649743 | 0.94 | DPP4 (0.65) | DPP4CHRM1 | |
| SCHEMBL1772989 | 0.90 | DPP4 (0.77) | DPP4CHRM1 | |
| SCHEMBL1772988 | 0.90 | DPP4 (0.77) | DPP4CHRM1 | |
| SCHEMBL19154444 | 0.85 | DPP4 (0.61) | DPP4CHRM1 | |
| SCHEMBL19305097 | 0.85 | DPP4 (0.65) | DPP4CHRM1 | |
| SCHEMBL20895842 | 0.83 | DPP4 (0.80) | DPP4CHRM1 | |
| SCHEMBL20895841 | 0.83 | DPP4 (0.80) | DPP4CHRM1 | |
| SCHEMBL19154408 | 0.83 | DPP4 (0.81) | DPP4CHRM1 | |
| SCHEMBL20895835 | 0.83 | DPP4 (0.81) | DPP4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190434-B1 | PURIN DERIVATIVES FOR USE IN THE TREATMENT OF FAP-RELATED DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2019-04-17 | — | — | EP | claimed |