Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699181 | 0.88 | TACR1 (0.48) | MEN1KMT2ATACR1CNR2ALOX15 | |
| SCHEMBL17078067 | 0.88 | MEN1 (0.51) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL973548 | 0.87 | MEN1 (0.52) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL17886665 | 0.85 | MEN1 (0.53) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL652130 | 0.85 | MEN1 (0.53) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL1002235 | 0.85 | SLC6A2 (0.52) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL1003431 | 0.84 | MEN1 (0.52) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL1206023 | 0.84 | TACR1 (0.53) | TACR1ALOX15TSHR | |
| SCHEMBL17886661 | 0.83 | MEN1 (0.51) | MEN1KMT2ASTSDRD2TACR1 | |
| SCHEMBL16565439 | 0.83 | MEN1 (0.51) | MEN1KMT2ASTSDRD2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116862-B1 | PIPERAZINE DERIVATIVES AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2019-04-17 | — | — | EP | disclosed |