SCHEMBL20902879

SCHEMBL20902879

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nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 11/20 0.44
DPP8 Q6V1X1 7/20 0.44
DPP9 Q86TI2 7/20 0.44
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 2/20 0.40
DPP7 Q9UHL4 6/20 0.40
IARS1 P41252 2/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30552158 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
SCHEMBL199059 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
SCHEMBL28599405 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
SCHEMBL29087496 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
SCHEMBL1685517 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
SCHEMBL13482942 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
SCHEMBL199058 1.00 DPP4 (0.44) DPP4DPP8DPP9ALOX15ALDH1A1
Hydrochloric Acid SCHEMBL2777940 0.98 DPP4 (0.43) DPP4DPP8DPP9ALOX15ALDH1A1
Hydrochloric Acid SCHEMBL29087500 0.98 DPP4 (0.43) DPP4DPP8DPP9ALOX15ALDH1A1
Hydrochloric Acid SCHEMBL4277313 0.98 DPP4 (0.43) DPP4DPP8DPP9ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192878-B2 Piperidine-2,6-dione derivative and use thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2021-12-07 US disclosed
US-20200062730-A1 NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF UBIX THERAPEUTICS, INC. (KR) 2020-02-27 US disclosed
EP-3036305-B1 COMPOUNDS WITH TERMINAL HETEROARYLCYANOVINYLENE GROUPS AND THEIR USE IN ORGANIC SOLAR CELLS BASF SE (DE) 2019-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062730-A1 NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF CRBN, PDCD11, CD47 DPP4 3828/4885DPP8 3422/4885DPP9 2919/4885
US-11192878-B2 Piperidine-2,6-dione derivative and use thereof CRBN, PDCD11, CD47 DPP4 3594/4885DPP8 3181/4885DPP9 2704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.