Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451205 | 1.00 | PLK1 (0.38) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL25835927 | 0.99 | TDP1 (0.38) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL29427520 | 0.96 | TDP1 (0.38) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL20904569 | 0.96 | TDP1 (0.38) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL29427451 | 0.96 | TDP1 (0.38) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL24401395 | 0.96 | TDP1 (0.38) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL24920306 | 0.94 | TDP1 (0.43) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL24297334 | 0.92 | PLK1 (0.34) | PLK1TDP1MEN1GAAKMT2A | |
| SCHEMBL21071149 | 0.92 | TDP1 (0.43) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL13759224 | 0.92 | TDP1 (0.43) | TDP1MEN1GAAKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11181521-B2 | Intra-droplet surface engineering to capture a molecular target | UNIVERSITE DE STRASBOURG (FR) | 2021-11-23 | — | — | US | disclosed |
| EP-3736572-A1 | INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET | Université de Strasbourg (FR) | 2020-11-11 | — | — | EP | disclosed |
| EP-3440463-B1 | INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET | UNIV STRASBOURG (FR) | 2020-07-08 | — | — | EP | disclosed |
| US-20190113509-A1 | INTRA-DROPLET SURFACE ENGINEERING TO CAPTURE A MOLECULAR TARGET | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-04-18 | — | — | US | disclosed |