Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150256 | 1.00 | MEN1 (0.35) | MEN1KMT2AACACBGABRA1GABRG2 | |
| SCHEMBL20907601 | 0.83 | MEN1 (0.38) | MEN1KMT2APTPN1MAPT | |
| SCHEMBL20907868 | 0.83 | EPHX2 (0.38) | MEN1KMT2APTPN1MAPT | |
| SCHEMBL28889780 | 0.83 | EPHX2 (0.38) | MEN1KMT2APTPN1MAPT | |
| SCHEMBL21150257 | 0.83 | MEN1 (0.38) | MEN1KMT2APTPN1MAPT | |
| SCHEMBL23114936 | 0.82 | MEN1 (0.31) | MEN1KMT2APTPN1 | |
| SCHEMBL29640250 | 0.82 | MEN1 (0.31) | MEN1KMT2APTPN1 | |
| SCHEMBL21150408 | 0.82 | MEN1 (0.31) | MEN1KMT2APTPN1 | |
| SCHEMBL21112384 | 0.82 | CYP1A2 (0.40) | MEN1KMT2AACACBGABRA1GABRG2 | |
| SCHEMBL21112387 | 0.82 | CYP1A2 (0.40) | MEN1KMT2AACACBGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075291-A1 | 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-04-18 | — | — | WO | disclosed |