Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20907565 | 0.81 | KMT2A (0.40) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL20908058 | 0.81 | KMT2A (0.40) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL20907785 | 0.78 | PTPN1 (0.40) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL28890354 | 0.78 | PTPN1 (0.40) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL20907818 | 0.77 | CYP2D6 (0.38) | MEN1KMT2AALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL21148934 | 0.77 | CYP2D6 (0.38) | MEN1KMT2AALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL22619411 | 0.76 | PTPN1 (0.38) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL20899678 | 0.76 | MEN1 (0.37) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL20907662 | 0.76 | PTPN1 (0.38) | MEN1KMT2AALDH1A1PTPN1MAPT | |
| SCHEMBL30557222 | 0.74 | BRD4 (0.35) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075291-A1 | 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-04-18 | — | — | WO | disclosed |