Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21148947 | 1.00 | MEN1 (0.33) | MEN1KMT2APTPN1LMNAHTT | |
| SCHEMBL29640222 | 1.00 | MEN1 (0.33) | MEN1KMT2APTPN1LMNAHTT | |
| SCHEMBL21150408 | 0.85 | MEN1 (0.31) | MEN1KMT2APTPN1 | |
| SCHEMBL29640250 | 0.85 | MEN1 (0.31) | MEN1KMT2APTPN1 | |
| SCHEMBL23114936 | 0.85 | MEN1 (0.31) | MEN1KMT2APTPN1 | |
| SCHEMBL20899783 | 0.83 | CYP1A2 (0.35) | MEN1KMT2A | |
| SCHEMBL30557356 | 0.83 | CYP1A2 (0.35) | MEN1KMT2A | |
| SCHEMBL21112711 | 0.83 | CYP1A2 (0.35) | MEN1KMT2A | |
| SCHEMBL20907590 | 0.82 | MEN1 (0.35) | MEN1KMT2APTPN1LMNAHTT | |
| SCHEMBL28407685 | 0.82 | MEN1 (0.35) | MEN1KMT2APTPN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |
| WO-2019075291-A1 | 1-BENZYL-2-IMINO-4-PHENYL-5-OXOIMIDAZOLIDINE DERIVATIVES AS HIV PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2019-04-18 | — | — | WO | disclosed |