Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | NCOR1 | O75376 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20900043 | 0.81 | SSTR3 (0.44) | SSTR3SCN9ACTSSCTSK | |
| SCHEMBL20900048 | 0.81 | SSTR3 (0.44) | SSTR3SCN9ACTSSCTSK | |
| SCHEMBL20900030 | 0.81 | SSTR3 (0.44) | SSTR3SCN9ACTSSCTSK | |
| SCHEMBL20910365 | 0.78 | HDAC3 (0.51) | HDAC3NCOR1HDAC1HDAC2HDAC8 | |
| SCHEMBL1351513 | 0.78 | SSTR3 (0.43) | SSTR3SCN9AHDAC3NCOR1HDAC1 | |
| SCHEMBL1351515 | 0.78 | SSTR3 (0.43) | SSTR3SCN9AHDAC3NCOR1HDAC1 | |
| SCHEMBL23788904 | 0.77 | SSTR3 (0.49) | SSTR3SCN9AHDAC3NCOR1HDAC1 | |
| SCHEMBL20910421 | 0.77 | KLK7 (0.46) | SSTR3CTSSCTSK | |
| SCHEMBL29473667 | 0.77 | KLK7 (0.46) | SSTR3CTSSCTSK | |
| SCHEMBL18481909 | 0.74 | SSTR3 (0.60) | SSTR3IDO1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019075252-A1 | PEPTIDOMIMETIC PROTEASOME INHIBITORS | CORNELL UNIVERSITY (US) | 2019-04-18 | — | — | WO | disclosed |