Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23979679 | 1.00 | TSHR (0.32) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL19771574 | 0.87 | TSHR (0.32) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18634260 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL24530128 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL21389594 | 0.81 | TSHR (0.34) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL22902679 | 0.76 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL21389610 | 0.76 | TSHR (0.34) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL20160857 | 0.76 | TSHR (0.30) | TSHR | |
| SCHEMBL18831048 | 0.74 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL26475940 | 0.73 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190112438-A1 | ANAEROBIC COMPOSITE MATRIX RESINS | TEXAS RESEARCH INTERNATIONAL, INC. (US) | 2019-04-18 | — | — | US | disclosed |