Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 3/20 | 0.58 |
| ▸ | ABL1 | P00519 | 2/20 | 0.58 |
| ▸ | ABL2 | P42684 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20912242 | 0.88 | SRC (0.76) | SRCMAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL20912366 | 0.86 | SRC (0.70) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL30628875 | 0.86 | SRC (0.65) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL20912251 | 0.86 | SRC (0.65) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL20911996 | 0.86 | SRC (0.65) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL20911998 | 0.86 | SRC (0.65) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL20911877 | 0.86 | SRC (0.65) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL20911833 | 0.85 | SRC (0.64) | SRCMAPTLMNAPOLBKDM4E | |
| SCHEMBL22604442 | 0.85 | SRC (1.00) | SRCLMNASMN1; SMN2EGFRKDR | |
| SCHEMBL20911997 | 0.84 | SRC (0.63) | SRCMAPTLMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073253-A1 | MAP4K4 INHIBITORS | IMPERIAL INNOVATIONS LIMITED (GB) | 2019-04-18 | — | — | WO | disclosed |