Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22604367 | 0.80 | SRC (0.57) | HPGDSEGFRTERTLMNAMAPT | |
| SCHEMBL20912266 | 0.71 | SRC (0.59) | PARP1EGFRLMNAMAPTKMT2A | |
| SCHEMBL22604421 | 0.67 | SRC (0.67) | EGFRLMNAMAPTKMT2ACDK2 | |
| SCHEMBL20912043 | 0.67 | PDPK1 (0.34) | PARP1 | |
| SCHEMBL20911666 | 0.65 | SRC (0.66) | LMNAMAPTKMT2ACDK2SRC | |
| SCHEMBL20912035 | 0.64 | FYN (0.42) | EGFRLMNAMAPTKMT2ASRC | |
| SCHEMBL13284736 | 0.63 | BACE1 (0.42) | KMT2A | |
| SCHEMBL22604454 | 0.62 | MAP4K4 (0.42) | PARP1EGFRLMNAMAPTKMT2A | |
| SCHEMBL20912264 | 0.62 | SRC (0.58) | LMNAMAPTKMT2ASRC | |
| SCHEMBL15607399 | 0.60 | ALK (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019073253-A1 | MAP4K4 INHIBITORS | IMPERIAL INNOVATIONS LIMITED (GB) | 2019-04-18 | — | — | WO | disclosed |