⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26835 | 0.83 | — | — | |
| SCHEMBL8805182 | 0.80 | — | — | |
| SCHEMBL7972453 | 0.78 | TSHR (0.30) | — | |
| SCHEMBL496590 | 0.75 | — | — | |
| SCHEMBL18623587 | 0.75 | CA1 (0.30) | — | |
| SCHEMBL8357678 | 0.75 | — | — | |
| SCHEMBL8357677 | 0.75 | — | — | |
| SCHEMBL355220 | 0.75 | — | — | |
| SCHEMBL14681015 | 0.75 | — | — | |
| SCHEMBL7311592 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788326-B1 | N-(PYRID-4-YL)AMIDES AND N-(PYRIMIDIN-4-YL)AMIDES AND THEIR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RES & DEV (FR) | 2019-04-24 | — | — | EP | disclosed |