Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 19/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20915952 | 1.00 | LPAR1 (0.49) | LPAR1LPAR2TAS1R3TAS1R1 | |
| SCHEMBL20915951 | 1.00 | LPAR1 (0.49) | LPAR1LPAR2TAS1R3TAS1R1 | |
| SCHEMBL19438575 | 0.92 | LPAR1 (0.54) | LPAR1LPAR2 | |
| SCHEMBL19438847 | 0.92 | LPAR1 (0.53) | LPAR1LPAR2 | |
| SCHEMBL20915895 | 0.92 | LPAR1 (0.53) | LPAR1LPAR2 | |
| SCHEMBL20915896 | 0.92 | LPAR1 (0.53) | LPAR1LPAR2 | |
| SCHEMBL19438699 | 0.84 | LPAR1 (0.58) | LPAR1LPAR2 | |
| SCHEMBL19438680 | 0.83 | LPAR1 (0.63) | LPAR1LPAR2 | |
| SCHEMBL19438538 | 0.83 | LPAR1 (0.66) | LPAR1LPAR2 | |
| SCHEMBL19438590 | 0.83 | LPAR1 (0.61) | LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119200-A1 | TERTIARY AMIDES AND METHOD OF USE | ABBVIE PHARMACEUTICAL TRADING (SHANGHAI) CO., LTD. (CN) | 2019-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119200-A1 | TERTIARY AMIDES AND METHOD OF USE | LPAR1, LPAR3, LPAR2 | LPAR1 1/4885LPAR2 3/4885TAS1R3 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.