SCHEMBL20917037

SCHEMBL20917037

C=C(C)C(C)(C)C(=O)C=C(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DEGS1 O15121 1/20 0.43
▸ NR4A1 P22736 1/20 0.40
▸ NR4A2 P43354 1/20 0.40
▸ NR4A3 Q92570 1/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ LMNA P02545 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ TP53 P04637 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ CES2 O00748 2/20 0.38
▸ CES1 P23141 2/20 0.38
▸ AKT1 P31749 1/20 0.37
▸ ATM Q13315 2/20 0.37
▸ MAPT P10636 1/20 0.37
▸ XBP1 P17861 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ EGFR P00533 1/20 0.37
▸ TDP1 Q9NUW8 2/20 0.36
▸ NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20917036 1.00 DEGS1 (0.43) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL20917231 1.00 DEGS1 (0.43) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL10716767 0.77 DEGS1 (0.46) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL5858029 0.77 NR4A1 (0.51) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL5858034 0.77 NR4A1 (0.51) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL20917112 0.76 CES1 (0.48) SMN1; SMN2LMNACES2CES1AKT1
Hydrochloric Acid SCHEMBL11760666 0.75 NR4A2 (0.58) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL6930945 0.74 DEGS1 (0.47) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL582234 0.73 NR4A2 (0.60) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2
SCHEMBL691911 0.73 NR4A2 (0.60) DEGS1NR4A1NR4A2NR4A3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3697878-B1 USE OF ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR AND COMPANY LTD (IN) 2026-01-28 — — EP disclosed
US-11549079-B2 Odorants and compositions comprising odorants S H KELKAR & COMPANY LIMITED 2023-01-10 — — US disclosed
US-11447715-B2 Odorants and compositions comprising odorants S H KELKAR & COMPANY LIMITED 2022-09-20 — — US disclosed
US-20210207059-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR & COMPANY LIMITED (IN) 2021-07-08 — — US disclosed
US-20200299611-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR & COMPANY LIMITED (IN) 2020-09-24 — — US disclosed
EP-3697878-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S. H. Kelkar&Company Pvt. Ltd. (IN) 2020-08-26 — — EP disclosed
EP-3697877-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S. H. Kelkar&Company Pvt. Ltd. (IN) 2020-08-26 — — EP disclosed
CN-111448299-A Odorants and compositions comprising odorants 丝趣科尔卡有限公司 2020-07-24 — — CN disclosed
CN-111433336-A Odorants and compositions comprising odorants 丝趣科尔卡有限公司 2020-07-17 — — CN disclosed
WO-2019076926-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR & COMPANY LIMITED (IN) 2019-04-25 — — WO disclosed
WO-2019076933-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS S H KELKAR & COMPANY LIMITED (IN) 2019-04-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210207059-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS DEK, OR10J3, THOC2 DEGS1 426/4885NR4A1 1908/4885NR4A2 1813/4885
US-20200299611-A1 ODORANTS AND COMPOSITIONS COMPRISING ODORANTS DEK, CAT, TAS2R41 DEGS1 372/4885NR4A1 3007/4885NR4A2 3081/4885
US-11549079-B2 Odorants and compositions comprising odorants DEK, CAT, TAS2R41 DEGS1 372/4885NR4A1 3007/4885NR4A2 3081/4885
US-11447715-B2 Odorants and compositions comprising odorants DEK, OR10J3, THOC2 DEGS1 426/4885NR4A1 1908/4885NR4A2 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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