Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20920098 | 1.00 | MAPK1 (0.60) | MAPK1AURKA | |
| SCHEMBL20931360 | 0.87 | MAPK1 (0.62) | MAPK1 | |
| SCHEMBL22284225 | 0.87 | MAPK1 (0.62) | MAPK1 | |
| SCHEMBL22284167 | 0.81 | MAPK1 (0.43) | MAPK1AURKA | |
| SCHEMBL22284231 | 0.81 | MAPK1 (0.43) | MAPK1AURKA | |
| SCHEMBL22298910 | 0.79 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL20916856 | 0.78 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL20916811 | 0.78 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL20931371 | 0.78 | MAPK1 (0.53) | MAPK1 | |
| SCHEMBL30554347 | 0.78 | MAPK1 (0.53) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110546150-B | Pyrazolyl-containing tricyclic derivatives, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-12-21 | — | — | CN | disclosed |
| EP-3699179-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2020-08-26 | — | — | EP | disclosed |
| CN-110546150-A | Pyrazolyl-containing tricyclic derivatives, preparation method and application thereof | JIANGSU HANSOH PHARMACEUTICAL GROUP CO LTD | 2019-12-06 | — | — | CN | disclosed |
| WO-2019076336-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏豪森药业集团有限公司 | 2019-04-25 | — | — | WO | disclosed |
| WO-2019076336-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏豪森药业集团有限公司 | 2019-04-25 | — | — | WO | disclosed |