Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 10/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18285335 | 0.90 | P2RY14 (0.52) | P2RY14RIPK1RAF1BRAFMCHR1 | |
| SCHEMBL20921564 | 0.86 | P2RY14 (0.37) | P2RY14RIPK1JAK2 | |
| SCHEMBL18285343 | 0.86 | P2RY14 (0.40) | P2RY14RIPK1RAF1BRAFJAK2 | |
| SCHEMBL18285370 | 0.84 | CNR1 (0.42) | P2RY14RIPK1JAK2 | |
| SCHEMBL18285291 | 0.83 | P2RY14 (0.52) | P2RY14RIPK1RAF1BRAFMCHR1 | |
| SCHEMBL18285309 | 0.79 | P2RY14 (0.41) | P2RY14RIPK1JAK2MAPTALOX5AP | |
| SCHEMBL18285304 | 0.77 | CNR1 (0.42) | P2RY14RIPK1JAK2KCNH2 | |
| SCHEMBL21841655 | 0.77 | P2RY14 (0.44) | P2RY14MCHR1JAK2POLBMAPT | |
| SCHEMBL18285306 | 0.76 | P2RY14 (0.51) | P2RY14RIPK1RAF1BRAFMCHR1 | |
| SCHEMBL18285293 | 0.75 | P2RY14 (0.40) | P2RY14RIPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303299-B1 | IMIDAZOLE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-04-24 | — | — | EP | disclosed |