Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KIT | P10721 | 5/20 | 0.54 |
| ▸ | ABL1 | P00519 | 5/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 5/20 | 0.54 |
| ▸ | BCR | P11274 | 4/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.51 |
| ▸ | CDK8 | P49336 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053459 | 0.90 | KIT (0.66) | KITABL1SRCBRAFCDK8 | |
| SCHEMBL14704589 | 0.90 | MKNK2 (0.65) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL14704590 | 0.90 | KIT (0.66) | KITABL1SRCBRAFCDK8 | |
| SCHEMBL2777943 | 0.88 | KIT (0.57) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL24403549 | 0.88 | ABL1 (0.53) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL28027108 | 0.88 | KIT (0.56) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL3166509 | 0.86 | KIT (0.51) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL28756487 | 0.85 | MKNK2 (0.51) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL4929396 | 0.85 | KIT (0.52) | KITABL1MKNK2BCRMKNK1 | |
| SCHEMBL27289083 | 0.84 | SRC (0.52) | KITABL1MKNK2BCRMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473624-A1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2019-04-24 | — | — | EP | disclosed |