Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | KIT | P10721 | 7/20 | 0.56 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28119359 | 0.87 | NR1H2 (0.55) | NR1H2KITDDR1BRAFKDM4E | |
| SCHEMBL374704 | 0.87 | NR1H2 (0.64) | NR1H2KITDDR1BRAFKDM4E | |
| SCHEMBL2707620 | 0.86 | NR1H2 (0.66) | NR1H2KITDDR1BRAFKDM4E | |
| SCHEMBL17316205 | 0.86 | NR1H2 (0.62) | NR1H2KITDDR1BRAFKDM4E | |
| Hydrochloric Acid SCHEMBL3561263 | 0.86 | NR1H2 (0.62) | NR1H2KITDDR1BRAFKDM4E | |
| Hydrochloric Acid SCHEMBL3559674 | 0.85 | NR1H2 (0.61) | NR1H2KITDDR1BRAFKDM4E | |
| SCHEMBL3931442 | 0.84 | NR1H2 (0.60) | NR1H2KITDDR1BRAFKDM4E | |
| SCHEMBL14704587 | 0.84 | KIT (0.63) | NR1H2KITDDR1BRAFEGFR | |
| SCHEMBL374710 | 0.82 | NR1H2 (0.57) | NR1H2KITDDR1BRAFKDM4E | |
| SCHEMBL17208715 | 0.82 | DDR1 (0.66) | NR1H2KITDDR1BRAFEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473624-B1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-05-11 | — | — | EP | disclosed |
| EP-3473624-A1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2019-04-24 | — | — | EP | disclosed |