Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.45 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20912688 | 0.94 | ABL1 (0.43) | ABL1BRAFCYP3A4KCNH2ROR1 | |
| SCHEMBL20912671 | 0.88 | ABL1 (0.44) | ABL1ABL2 | |
| SCHEMBL9610746 | 0.83 | ABL1 (0.50) | ABL1BRAFKIT | |
| SCHEMBL20922059 | 0.81 | BRAF (0.44) | ABL1BRAF | |
| SCHEMBL24403508 | 0.80 | ABL1 (0.45) | ABL1ABL2BRAF | |
| SCHEMBL589268 | 0.79 | ABL1 (0.56) | ABL1ABL2ROR1 | |
| SCHEMBL20912667 | 0.79 | FLT3 (0.40) | ABL1KIT | |
| SCHEMBL20912748 | 0.78 | ABL1 (0.41) | ABL1BRAF | |
| SCHEMBL20921950 | 0.77 | ABL1 (0.57) | ABL1KIT | |
| SCHEMBL24403450 | 0.77 | KIT (0.49) | ABL1ROR1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473624-A1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2019-04-24 | — | — | EP | disclosed |