Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.71 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20923991 | 0.84 | KDM1A (0.71) | KDM1AGRM5NPC1RAB9A | |
| SCHEMBL6837416 | 0.83 | KDM1A (1.00) | KDM1A | |
| SCHEMBL527719 | 0.83 | KDM1A (1.00) | KDM1A | |
| SCHEMBL20924215 | 0.83 | KDM1A (0.73) | KDM1ADHODH | |
| SCHEMBL527718 | 0.83 | KDM1A (1.00) | KDM1A | |
| Hydrochloric Acid SCHEMBL15137188 | 0.82 | KDM1A (0.98) | KDM1A | |
| Hydrochloric Acid SCHEMBL15137187 | 0.82 | KDM1A (0.98) | KDM1A | |
| SCHEMBL20924173 | 0.81 | KDM1A (0.70) | KDM1ADHODH | |
| SCHEMBL18923960 | 0.81 | KDM1A (0.73) | KDM1AGRM5NPC1RAB9A | |
| SCHEMBL20924260 | 0.80 | RXFP1 (0.51) | KDM1ANPC1RAB9ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |