Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.66 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924258 | 0.81 | KDM1A (0.44) | KDM1AKMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL6837420 | 0.80 | KDM1A (0.47) | KDM1AKMT2AL3MBTL1CYP2A6MAOB | |
| SCHEMBL6837343 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL527019 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| SCHEMBL527020 | 0.80 | KDM1A (1.00) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL15136923 | 0.78 | KDM1A (0.97) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL15136924 | 0.78 | KDM1A (0.97) | KDM1AMAOB | |
| SCHEMBL20924181 | 0.76 | KDM1A (0.68) | KDM1AKMT2AL3MBTL1KDM4EGLA | |
| SCHEMBL14018446 | 0.75 | KDM1A (0.59) | KDM1ACYP11B1CYP11B2KMT2AL3MBTL1 | |
| SCHEMBL20924267 | 0.72 | KDM1A (0.64) | KDM1AALDH1A1MAOBDEGS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-B1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2019-04-24 | — | — | EP | disclosed |