Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.50 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924538 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL14605324 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL13405030 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL16004352 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924393 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924349 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924398 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924576 | 1.00 | POLB (0.56) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL16156403 | 0.95 | POLB (0.55) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL18476023 | 0.94 | POLB (0.65) | POLBFUT5P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961388-B1 | DRUG COMBINATIONS | ASTEX PHARMACEUTICALS INC (US) | 2019-04-24 | — | — | EP | disclosed |