⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14449825 | 0.72 | — | — | |
| SCHEMBL25013267 | 0.72 | — | — | |
| SCHEMBL14301395 | 0.70 | — | — | |
| SCHEMBL14437331 | 0.68 | — | — | |
| SCHEMBL23331966 | 0.68 | — | — | |
| SCHEMBL18819476 | 0.67 | — | — | |
| SCHEMBL24784877 | 0.67 | — | — | |
| SCHEMBL21369357 | 0.67 | — | — | |
| SCHEMBL15868237 | 0.64 | — | — | |
| SCHEMBL23396661 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079649-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | BLUEPRINT MEDICINES CORPORATION (US) | 2019-04-25 | — | — | WO | disclosed |