SCHEMBL20929751

SCHEMBL20929751

CN1C[C@H]2CC1CN2c1ccc(Cl)nn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 10/20 0.62
KCNH2 Q12809 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26081879 1.00 CHRNA7 (0.62) CHRNA7KCNH2
SCHEMBL5389366 1.00 CHRNA7 (0.62) CHRNA7KCNH2
SCHEMBL5037219 1.00 CHRNA7 (0.62) CHRNA7KCNH2
SCHEMBL5034167 0.83 CHRNA7 (0.46) CHRNA7KCNH2
SCHEMBL611306 0.81 CHRNA7 (0.62) CHRNA7KCNH2
SCHEMBL21262667 0.77 CHRNA7 (0.64) CHRNA7KCNH2
SCHEMBL6627648 0.77 CHRNA7 (1.00) CHRNA7KCNH2
SCHEMBL4109514 0.77 CHRNA7 (1.00) CHRNA7KCNH2
SCHEMBL4109510 0.77 CHRNA7 (1.00) CHRNA7KCNH2
SCHEMBL4109513 0.77 CHRNA7 (1.00) CHRNA7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265254-A2 IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS Galapagos N.V. (BE) 2023-10-25 EP disclosed
EP-3697784-B1 IMIDAZO[4,5-B]PYRIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS GALAPAGOS NV (BE) 2023-10-04 EP disclosed
WO-2019076716-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS GALAPAGOS NV (BE) 2019-04-25 WO disclosed