SCHEMBL20933128

SCHEMBL20933128

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4-c4ccc5c(c4)Oc4ccc6c(c4O5)-c4ccccc4C6(C)C)n3)cc21

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.30
RARB P10826 1/20 0.30
RARG P13631 1/20 0.30
RXRA P19793 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20933417 1.00 BACE1 (0.30) BACE1RARBRARGRXRAADORA2A
SCHEMBL20934112 0.96 ADORA2A (0.32) BACE1ADORA2AADORA1
SCHEMBL20933981 0.96 ADORA2A (0.32) BACE1ADORA2AADORA1
SCHEMBL20933545 0.95 BACE1 (0.31) BACE1RARBRARGRXRAADORA2A
SCHEMBL20934010 0.95 BACE1 (0.31) BACE1RARBRARGRXRAADORA2A
SCHEMBL20933308 0.94 PDK2 (0.34) BACE1ADORA2AADORA1
SCHEMBL20933543 0.94 BACE1 (0.30) BACE1RARBRARGRXRAADORA2A
SCHEMBL20934015 0.94 BACE1 (0.30) BACE1RARBRARGRXRAADORA2A
SCHEMBL20933553 0.94 RARB (0.32) BACE1RARBRARGRXRAADORA2A
SCHEMBL20933411 0.94 HSD17B10 (0.32) RARBRARGRXRAADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed