SCHEMBL20933167

SCHEMBL20933167

c1ccc(-c2nc(-c3ccc(-c4cccc5c4Oc4c(ccc6c4-c4ccccc4C6(c4ccccc4)c4ccccc4)O5)cc3)cc(-c3ccc4ccccc4c3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 3/20 0.34
HPGD P15428 3/20 0.34
LMNA P02545 2/20 0.34
GLA P06280 1/20 0.34
CYP1A2 P05177 2/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NTSR1 P30989 1/20 0.32
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
CTRC Q99895 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20933842 0.95 CYP1A1 (0.37) CYP1A1CYP1B1MEN1KMT2AALDH1A1
SCHEMBL20933349 0.94 CYP1A1 (0.36) CYP1A1CYP1B1MEN1KMT2AALDH1A1
SCHEMBL20933166 0.94 MAPT (0.36) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL20934315 0.94 CYP1A1 (0.34) CYP1A1CYP1B1MEN1KMT2AALDH1A1
SCHEMBL20934024 0.94 CYP1A1 (0.36) CYP1A1CYP1B1MEN1KMT2AALDH1A1
SCHEMBL20933591 0.93 KDM4E (0.34) MEN1KMT2AALDH1A1KDM4ECYP1A2
SCHEMBL20933314 0.93 KMT2A (0.32) CYP1A1CYP1B1MEN1KMT2AALDH1A1
SCHEMBL20933162 0.93 MEN1 (0.35) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL20933158 0.92 MEN1 (0.34) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL20933316 0.91 MEN1 (0.34) MEN1KMT2AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed