SCHEMBL20933221

SCHEMBL20933221

Clc1ccc2c(c1)Oc1c(ccc3c1-c1ccccc1C3(c1ccccc1)c1ccccc1)O2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.44
MAP3K14 Q99558 1/20 0.38
MAPK1 P28482 1/20 0.35
PDK2 Q15119 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
OPRK1 P41145 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
CFTR P13569 1/20 0.31
GOPC Q9HD26 1/20 0.31
FTO Q9C0B1 2/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20933263 1.00 AHR (0.44) AHRMAP3K14MAPK1PDK2MEN1
SCHEMBL23546526 0.91 AHR (0.37) AHRMAP3K14MAPK1MEN1MAPT
SCHEMBL23546516 0.88 AHR (0.39) AHRMAPK1MEN1MAPTKMT2A
SCHEMBL20934247 0.88 MEN1 (0.39) AHRMAPK1MEN1MAPTKMT2A
SCHEMBL23546575 0.88 AHR (0.35) AHRMAPK1PDK2MEN1MAPT
SCHEMBL20940733 0.85 KDM4E (0.33) MEN1MAPTKMT2AKDM4ELMNA
SCHEMBL20933259 0.82 AHR (0.49) AHRPDK2MEN1MAPTKMT2A
SCHEMBL20933258 0.82 AHR (0.46) AHRMAPK1PDK2MEN1MAPT
SCHEMBL20934046 0.82 AHR (0.46) AHRMAPK1PDK2MEN1MAPT
SCHEMBL20940662 0.81 AHR (0.47) AHRPDK2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed