SCHEMBL20933359

SCHEMBL20933359

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)Oc3ccc5c(c3O4)-c3ccccc3C5(c3ccccc3)c3ccccc3)n2)cc1

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
MAPT P10636 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
OPRK1 P41145 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
PKM P14618 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20934068 1.00 MEN1 (0.32) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20934055 0.99 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20933827 0.99 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20934063 0.99 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20933817 0.99 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20933639 0.97 KDM4E (0.30) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20934526 0.97 KDM4E (0.30) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20933825 0.97 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20933627 0.97 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E
SCHEMBL20933610 0.97 MEN1 (0.31) MEN1KMT2AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed