Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 14/20 | 0.53 |
| ▸ | TDO2 | P48775 | 6/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22274304 | 0.94 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL22568198 | 0.90 | IDO1 (0.65) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL20935325 | 0.90 | IDO1 (0.65) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL20935352 | 0.88 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL21289727 | 0.88 | IDO1 (0.50) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL31241547 | 0.87 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL21289773 | 0.87 | IDO1 (0.53) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL20935350 | 0.86 | IDO1 (0.55) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL22568207 | 0.86 | IDO1 (0.55) | IDO1TDO2CYP2C9CYP2C8CYP3A4 | |
| SCHEMBL20935348 | 0.85 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP2C8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078968-A2 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | ANGEX PHARMACEUTICAL, INC. (US) | 2019-04-25 | — | — | WO | disclosed |