Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 15/20 | 0.62 |
| ▸ | IKZF1 | Q13422 | 6/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765355 | 0.92 | IKZF2 (0.74) | IKZF2IKZF1 | |
| Hydrochloric Acid SCHEMBL21340291 | 0.91 | IKZF2 (0.73) | IKZF2IKZF1 | |
| SCHEMBL26552787 | 0.91 | IKZF1 (0.66) | IKZF2IKZF1 | |
| SCHEMBL25617053 | 0.89 | IKZF1 (0.64) | IKZF2IKZF1 | |
| SCHEMBL24790253 | 0.89 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL25624573 | 0.89 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL24789318 | 0.89 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL25617951 | 0.87 | IKZF2 (0.63) | IKZF2IKZF1 | |
| SCHEMBL25615917 | 0.87 | IKZF2 (0.63) | IKZF2IKZF1 | |
| SCHEMBL20936128 | 0.87 | IKZF2 (0.59) | IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079569-A1 | COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION | NOVARTIS AG (CH) | 2019-04-25 | — | — | WO | disclosed |