SCHEMBL20936231

SCHEMBL20936231

Cc1cc(F)c(C(F)(F)Oc2ccc(-c3ccc4c(F)c(F)c(F)cc4c3)c(F)c2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
GRM2 Q14416 1/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
GPR3 P46089 1/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
FFAR4 Q5NUL3 3/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31
GRIN2B Q13224 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20202946 0.89 ALOX5AP (0.39) ALOX5APFEN1GRM2ESR1ESR2
SCHEMBL20202931 0.87 ALOX5AP (0.38) ALOX5APFEN1GRM2ESR1ESR2
SCHEMBL18193773 0.87 ALOX5AP (0.36) ALOX5APFEN1GRM2GPR3
SCHEMBL20202933 0.85 ALOX5AP (0.36) ALOX5APFEN1GRM2FFAR4AKR1C3
SCHEMBL20202932 0.84 RARB (0.37) ALOX5APFEN1GRM2FFAR4AKR1C3
SCHEMBL10021838 0.83 ALOX5AP (0.38) ALOX5APFEN1GRM2GPR3FFAR4
SCHEMBL18193774 0.82 CYP11B1 (0.32) ALOX5APFEN1GPR3
SCHEMBL20005280 0.82
SCHEMBL17075778 0.81 ALOX5AP (0.34) ALOX5APFEN1GRM2AKR1C3AKR1C2
SCHEMBL20202968 0.81 ALOX5AP (0.35) ALOX5APFEN1GRM2AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed