Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.46 |
| ▸ | CA2 | P00918 | 9/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851265 | 0.90 | CA1 (0.58) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL8076402 | 0.79 | CA1 (0.62) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL20919996 | 0.75 | CA1 (0.79) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL20936501 | 0.72 | GAA (0.46) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL20936500 | 0.71 | MAPT (0.41) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL20788610 | 0.70 | CA1 (0.59) | CA1CA2CA9CA12CA4 | |
| SCHEMBL23219874 | 0.69 | CA1 (0.58) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL12317636 | 0.69 | CA1 (0.69) | CA1CA2CA9CA12CA4 | |
| SCHEMBL20936552 | 0.69 | CA1 (0.53) | CA1CA2CA9CA12PDE4A | |
| SCHEMBL24526218 | 0.69 | CA1 (0.53) | CA1CA2CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079357-A1 | TNIK MODULATORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2019-04-25 | — | — | WO | disclosed |