⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20937570 | 0.77 | — | — | |
| SCHEMBL20937951 | 0.75 | — | — | |
| SCHEMBL19240655 | 0.74 | — | — | |
| SCHEMBL17850467 | 0.70 | — | — | |
| SCHEMBL26288076 | 0.63 | — | — | |
| SCHEMBL12654498 | 0.60 | — | — | |
| SCHEMBL30491566 | 0.60 | GAA (0.31) | — | |
| SCHEMBL22993466 | 0.59 | — | — | |
| SCHEMBL14431943 | 0.59 | — | — | |
| SCHEMBL26286369 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464949-B2 | Thiazolyl-containing compounds for treating proliferative diseases | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20190119301-A1 | THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-04-25 | — | — | US | disclosed |