Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21128303 | 0.86 | NPSR1 (0.44) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL17591873 | 0.81 | NPSR1 (0.47) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL348236 | 0.81 | NPSR1 (0.63) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL16019090 | 0.81 | NPSR1 (0.47) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL8579928 | 0.81 | NPSR1 (0.63) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL4576754 | 0.81 | NPSR1 (0.63) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL17591872 | 0.81 | NPSR1 (0.47) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL27400275 | 0.81 | NPSR1 (0.47) | NPSR1ALOX15GLO1ALDH1A1CYP2D6 | |
| SCHEMBL3357035 | 0.78 | — | — | |
| SCHEMBL6819424 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079119-A1 | SULPHONAMIDES AND COMPOSITIONS THEREOF FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | IFM Tre, Inc. (US) | 2019-04-25 | — | — | WO | disclosed |