Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22584678 | 1.00 | ACACB (0.44) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22584676 | 1.00 | ACACB (0.44) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20916932 | 1.00 | ACACB (0.44) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20939112 | 0.86 | GRIN2B (0.37) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22584315 | 0.86 | GRIN2B (0.37) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22584319 | 0.86 | GRIN2B (0.37) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22584140 | 0.84 | IDO1 (0.44) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL22584142 | 0.84 | IDO1 (0.44) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20916883 | 0.84 | IDO1 (0.44) | ACACBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30073690 | 0.84 | IDO1 (0.44) | ACACBPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019076358-A1 | HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF | JS INNOPHARM (SHANGHAI) LTD (CN) | 2019-04-25 | — | — | WO | disclosed |