SCHEMBL20940658

SCHEMBL20940658

Brc1ccc2c(c1)Oc1c(ccc3c1-c1ccccc1C31c3ccccc3-c3ccccc31)O2

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.51
PDK2 Q15119 1/20 0.35
SIRT1 Q96EB6 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
CYP2C19 P33261 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
SMAD3 P84022 1/20 0.30
KMT2A Q03164 1/20 0.30
PRMT1 Q99873 1/20 0.30
ACE2 Q9BYF1 1/20 0.30
FTO Q9C0B1 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20940661 1.00 AHR (0.51) AHRPDK2SIRT1OPRM1OPRD1
SCHEMBL20940662 0.84 AHR (0.47) AHRPDK2MEN1MAPTHPGD
SCHEMBL20941105 0.83 AHR (0.31) AHRMEN1MAPTHPGDCYP2C19
SCHEMBL20941133 0.82 AHR (0.58) AHRPDK2SIRT1OPRM1OPRD1
SCHEMBL20942088 0.82 AHR (0.58) AHRPDK2SIRT1OPRM1OPRD1
SCHEMBL29651964 0.82 AHR (0.50) AHRPDK2SIRT1OPRM1OPRD1
SCHEMBL20940657 0.80 PDK2 (0.37) AHRPDK2MEN1MAPTKMT2A
SCHEMBL21305014 0.79 AHR (0.52) AHRPDK2SIRT1OPRM1OPRD1
SCHEMBL30913037 0.79 AHR (0.52) AHRPDK2SIRT1OPRM1OPRD1
SCHEMBL20940301 0.79 PDK2 (0.36) AHRPDK2PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078443-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed