⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL5831159 | 0.80 | TSHR (0.43) | — | |
| SCHEMBL25344425 | 0.78 | — | — | |
| SCHEMBL11474499 | 0.78 | — | — | |
| Methyl Alcohol SCHEMBL10893106 | 0.75 | — | — | |
| Methyl Alcohol SCHEMBL27523245 | 0.75 | — | — | |
| Methyl Alcohol SCHEMBL27914354 | 0.75 | — | — | |
| Acetic Acid SCHEMBL4254871 | 0.75 | — | — | |
| Ethane SCHEMBL5590416 | 0.72 | — | — | |
| Fluoromethane SCHEMBL28011400 | 0.72 | — | — | |
| Ethane SCHEMBL18837989 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671803-B | Cross-linked electronic regulating layer material, preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2024-06-18 | — | — | CN | disclosed |
| CN-114671803-A | Cross-linked electronic regulating layer material, preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2022-06-28 | — | — | CN | disclosed |
| EP-3476829-B1 | BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME | UNIV FUDAN (CN) | 2021-12-15 | — | — | EP | disclosed |
| US-10851050-B2 | Biaryl urea derivative or salt thereof and preparation process and use for the same | FUDAN UNIVERSITY (CN) | 2020-12-01 | — | — | US | disclosed |
| CN-107522634-B | Biaryl urea carboxylic acid derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2020-09-01 | — | — | CN | disclosed |
| US-20200239411-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME | UNIV FUDAN (CN) | 2020-07-30 | — | — | US | disclosed |
| US-10647665-B2 | Biaryl urea derivative or salt thereof and preparation process and use for the same | FUDAN UNIVERSITY (CN) | 2020-05-12 | — | — | US | disclosed |
| CN-107522641-B | Biaryl urea derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2020-05-05 | — | — | CN | disclosed |
| US-20190248737-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF AND PREPARATION PROCESS AND USE FOR THE SAME | FUDAN UNIVERSITY (CN) | 2019-08-15 | — | — | US | disclosed |
| EP-3476829-A1 | BIARYL UREA DERIVATIVE OR SALT THEREOF, AND MANUFACTURING AND APPLICATION OF SAME | Fudan University (CN) | 2019-05-01 | — | — | EP | disclosed |
| CN-1968929-B | Substituted tetrahydro-2h-isoquinolin-1-one derivatives, method for the production thereof, and use of the same as medicaments | SANOFI AVENTIS DEUTSCHLAND | 2010-09-08 | — | — | CN | disclosed |