Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631770 | 1.00 | TDP1 (0.63) | TDP1RXRA | |
| SCHEMBL30631771 | 1.00 | TDP1 (0.63) | TDP1RXRA | |
| SCHEMBL15413091 | 0.83 | TDP1 (0.45) | TDP1RXRA | |
| SCHEMBL30631769 | 0.81 | TDP1 (0.47) | TDP1RXRA | |
| SCHEMBL20944818 | 0.81 | TDP1 (0.47) | TDP1RXRA | |
| SCHEMBL16312049 | 0.80 | TDP1 (0.70) | TDP1RXRA | |
| SCHEMBL30631773 | 0.80 | TDP1 (0.68) | TDP1RXRA | |
| SCHEMBL2604424 | 0.80 | TDP1 (0.83) | TDP1RXRA | |
| SCHEMBL4458946 | 0.80 | TDP1 (0.68) | TDP1RXRA | |
| SCHEMBL16312041 | 0.80 | TDP1 (0.78) | TDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336704-B2 | Method for preparing indenoisoquinoline derivatives | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2019-07-02 | — | — | US | disclosed |
| US-20190127330-A1 | Method for Preparing Indenoisoquinoline Derivatives | NATIONAL TAIWAN NORMAL UNIVERSITY (TW) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336704-B2 | Method for preparing indenoisoquinoline derivatives | CYP1A2, RECQL, RDX | TDP1 3167/4885RXRA 1260/4885 |
| US-20190127330-A1 | Method for Preparing Indenoisoquinoline Derivatives | CYP1A2, RECQL, RDX | TDP1 3167/4885RXRA 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.