SCHEMBL209481

SCHEMBL209481

O=[C]NCCF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514396 0.81
SCHEMBL5651689 0.79
SCHEMBL5473399 0.78
SCHEMBL5653685 0.77
SCHEMBL5650753 0.77
SCHEMBL209664 0.73
SCHEMBL5651322 0.73
SCHEMBL513714 0.72
SCHEMBL3583741 0.72
SCHEMBL5651243 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101970394-B Novel cyclic hydrocarbon compounds for the treatment of diseases LEO PHARMA AS 2015-05-27 CN claimed
CN-103705509-A Isoxazoline compositions and their use as antiparasitics INTERVET INT BV 2014-04-09 CN claimed
US-20100305140-A1 BENZIMIDAZOLE DERIVATIVES WHICH ARE TO BE USED AS ANTAGONIST FOR THE CB1-RECEPTOR ASTRAZENECA AB (SE) 2010-12-02 US claimed
CN-101778566-A Isoxazoline compositions and their use as antiparasitics INTERVET INT BV 2010-07-14 CN claimed
EP-2035409-A1 BENZIMIDAZOLE DERIVATIVES WHICH ARE TO BE USED AS ANATGONIST FOR THE CB1-RECEPTOR AstraZeneca AB (SE) 2009-03-18 EP claimed
EP-2010526-A1 BENZIMIDAZOLE 5-SULFONAMIDE DERIVATIVES AS CANNABINOID 1 (CB1) RECEPTOR LIGANDS AstraZeneca AB (SE) 2009-01-07 EP claimed
WO-2007145563-A1 BENZIMIDAZOLE DERIVATIVES WHICH ARE TO BE USED AS ANTAGONIST FOR THE CB1-RECEPTOR ASTRAZENECA AB (SE) 2007-12-21 WO claimed
WO-2007120101-A1 BENZIMIDAZOLE 5-SULFONAMIDE DERIVATIVES AS CANNABINOID 1 (CB1) RECEPTOR LIGANDS ASTRAZENECA AB (SE) 2007-10-25 WO claimed
US-20070244092-A1 N-Cyclopropyl-1-{[2-(1,1-difluoroethyl)-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]sulfonyl}-1H-pyrrole-3-carboxamide; for pain management ASTRAZENECA AB (SE) 2007-10-18 US claimed
US-20070049620-A1 Cyclic tertiary amine compound SANKYO COMPANY, LIMITED (JP) 2007-03-01 US claimed
EP-1632488-A1 CYCLIC TERTIARY AMINE COMPOUND Sankyo Company, Limited (JP) 2006-03-08 EP claimed
EP-3957627-B1 6-MEMBERED HETEROCYCLIC DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SHIONOGI & CO (JP) 2024-06-19 EP disclosed
WO-2024114814-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS ONQUALITY PHARMACEUTICALS CHINA LTD (CN) 2024-06-06 WO disclosed
WO-2024048778-A1 ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT 日産化学株式会社 2024-03-07 WO disclosed
EP-4317160-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Kumiai Chemical Industry Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-0897385-A1 HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-02-24 EP disclosed
EP-0897384-A1 HERBICIDAL BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-02-24 EP disclosed
WO-1997038996-A1 HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1997-10-23 WO disclosed
WO-1997038988-A1 HERBICIDAL HETEROCYCLICALLY ANNULATED BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1997-10-23 WO disclosed
WO-1997038987-A1 HERBICIDAL BENZOYLISOTHIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1997-10-23 WO disclosed