⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5816521 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL14763821 | 0.98 | — | — | |
| SCHEMBL673578 | 0.68 | — | — | |
| SCHEMBL917042 | 0.68 | — | — | |
| SCHEMBL4057592 | 0.67 | — | — | |
| SCHEMBL10920033 | 0.67 | — | — | |
| SCHEMBL3576495 | 0.65 | — | — | |
| SCHEMBL14471595 | 0.65 | — | — | |
| SCHEMBL9688112 | 0.65 | — | — | |
| SCHEMBL29102107 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220233501-A1 | THERAPEUTIC COMBINATIONS | SUPERSALUS INC (US) | 2022-07-28 | — | — | US | claimed |
| WO-2020167748-A1 | THERAPEUTIC COMBINATIONS | SUPERSALUS, INC. (US) | 2020-08-20 | — | — | WO | claimed |
| US-20200253926-A1 | THERAPEUTIC COMBINATIONS | SUPERSALUS, INC. | 2020-08-13 | — | — | US | claimed |
| CN-109596756-A | Detection method in relation to substance in a kind of composition and Pramipexole starting material | 成都倍特药业有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-109232471-A | A kind of preparation method of body of Pramipexole dihydrochloride | 安徽省庆云医药股份有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-107868063-A | A kind of acetone 9 oxime derivate of tetrahydro benzothiazol 2 and its preparation method and application | 泰山医学院 | 2018-04-03 | — | — | CN | claimed |
| CN-105936628-B | The synthetic method of body of Pramipexole dihydrochloride intermediate | 赤峰赛林泰药业有限公司 | 2018-03-27 | — | — | CN | claimed |
| CN-107540633-A | A kind of industrialized process for preparing of Pramipexole and its hydrochloride | 江苏神龙药业有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-105753812-B | The synthetic method of body of Pramipexole dihydrochloride intermediate | 赤峰赛林泰药业有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-104496936-B | A kind of preparation method of body of Pramipexole dihydrochloride | 海南康虹医药科技开发有限公司 | 2017-11-28 | — | — | CN | claimed |
| US-4650515-A | IMIDAZOLIDINONES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-03-17 | — | — | US | claimed |
| EP-0186087-A1 | Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs | Dr. Karl Thomae GmbH (DE) | 1986-07-02 | — | — | EP | claimed |
| US-4577029-A | Derivative of tetrahydrobenzothiazole and herbicidal composition containing the same as active ingredient | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-03-18 | — | — | US | claimed |
| US-4561877-A | Derivatives of tetrahydrobenzothiazole and herbicidal compositions containing the same as active ingredient | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | claimed |
| US-4551168-A | Herbicidal 2-(1,3,5-1H-triazin-2-one)-tetrahydrobenzothiazole derivatives, and compositions therefor | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-11-05 | — | — | US | claimed |
| EP-0125029-A1 | Herbicidal tetrahydro benzothiazole derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-11-14 | — | — | EP | claimed |
| US-4481027-A | POSTEMERGENCE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-11-06 | — | — | US | claimed |
| EP-0122761-A2 | Herbicidal tetrahydrobenzothiazole derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-24 | — | — | EP | claimed |
| EP-0122130-A2 | Herbicidal tetrahydrobenzothiazole derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-17 | — | — | EP | claimed |
| US-3970461-A | Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |