Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.67 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.58 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033866 | 0.80 | KDM4C (0.69) | KDM4CKDM2BPHF8MAPK14 | |
| SCHEMBL20953962 | 0.80 | KDM4C (0.72) | KDM4CKDM2BPHF8POLB | |
| SCHEMBL16033821 | 0.80 | KDM4C (1.00) | KDM4CKDM2BPHF8KDM5B | |
| SCHEMBL16033932 | 0.79 | KDM4C (1.00) | KDM4CKDM2BKDM5B | |
| SCHEMBL20953947 | 0.75 | PHF8 (0.62) | KDM4CKDM2BPHF8KDM5BKDM2A | |
| SCHEMBL20978965 | 0.75 | KDM4C (0.72) | KDM4CKDM2BPHF8KDM5BMAPK14 | |
| SCHEMBL16033723 | 0.74 | KDM4C (1.00) | KDM4CKDM2BPHF8MAPK14POLB | |
| SCHEMBL16033760 | 0.74 | KDM4C (1.00) | KDM4CKDM2BPHF8MAPK14POLB | |
| SCHEMBL16033547 | 0.72 | KDM4C (1.00) | KDM4CKDM2BKDM5B | |
| SCHEMBL19101732 | 0.72 | KDM4C (0.72) | KDM4CKDM2BKDM5BMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | claimed |