Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.69 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.69 |
| ▸ | KDM5A | P29375 | 6/20 | 0.58 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20953950 | 0.89 | KDM4C (0.69) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL16034053 | 0.82 | KDM4C (1.00) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL20953951 | 0.82 | KDM4C (0.71) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL16033764 | 0.81 | KDM4C (1.00) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL16033542 | 0.80 | KDM4C (1.00) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL20953971 | 0.80 | KDM4C (0.81) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL17604505 | 0.76 | KDM4C (0.79) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL24244236 | 0.74 | KDM4C (0.65) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL16034058 | 0.73 | KDM4C (1.00) | KDM4CKDM2BKDM5APHF8KDM2A | |
| SCHEMBL16034250 | 0.73 | KDM4C (0.64) | KDM4CKDM2BKDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | claimed |