Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.73 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.73 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.69 |
| ▸ | KDM2B | Q8NHM5 | 12/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035025 | 0.84 | KDM4C (1.00) | KDM4CKDM5BPHF8KDM2B | |
| SCHEMBL24244195 | 0.83 | PHF8 (0.69) | KDM4CKDM5BPHF8KDM2BCYP19A1 | |
| SCHEMBL16034561 | 0.82 | KDM2B (0.64) | KDM4CKDM5BPHF8KDM2B | |
| SCHEMBL17604549 | 0.81 | KDM4C (0.73) | KDM4CKDM5BPHF8KDM2BCYP19A1 | |
| SCHEMBL20953953 | 0.81 | KDM4C (0.62) | KDM4CKDM5BPHF8KDM2B | |
| SCHEMBL20953954 | 0.81 | KDM4C (0.62) | KDM4CKDM5BPHF8KDM2B | |
| SCHEMBL17693185 | 0.79 | KDM5B (0.70) | KDM4CKDM5BPHF8KDM2BCYP19A1 | |
| SCHEMBL17693184 | 0.79 | KDM5B (0.70) | KDM4CKDM5BPHF8KDM2BCYP19A1 | |
| SCHEMBL17898917 | 0.79 | KDM5B (0.70) | KDM4CKDM5BPHF8KDM2BCYP19A1 | |
| SCHEMBL16033935 | 0.79 | KDM4C (1.00) | KDM4CKDM5BPHF8KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | claimed |