Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL20958243

CCCC(=O)Oc1ccccc1.N

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.57
CTNNB1 P35222 1/20 0.57
KMT2A Q03164 8/20 0.52
ALDH1A1 P00352 4/20 0.52
MAPT P10636 3/20 0.52
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ELANE P08246 1/20 0.51
ESR1 P03372 3/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.47
RECQL P46063 1/20 0.47
CYP19A1 P11511 1/20 0.47
PDGFRB P09619 1/20 0.47
PDGFRA P16234 1/20 0.47
CES2 O00748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62921 0.98 BCL9 (0.59) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL20769806 0.98 BCL9 (0.59) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL29351783 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL29272537 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
Iodide SCHEMBL11482340 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL31053164 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL19888719 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL31053173 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
SCHEMBL11134912 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT
Ethane SCHEMBL27661050 0.96 BCL9 (0.57) BCL9CTNNB1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462816-A Hecogenin derivative with antitumor activity and preparation method and application thereof 齐齐哈尔医学院 2025-02-18 CN disclosed
CN-119462816-A Hecogenin derivative with antitumor activity and preparation method and application thereof 齐齐哈尔医学院 2025-02-18 CN disclosed
CN-118598788-A New pyrrole-2, 5-diketone xyloconstructed keto acid compound and preparation method and application thereof 华北制药集团新药研究开发有限责任公司 2024-09-06 CN disclosed
CN-110753755-B T cell depletion state specific gene expression regulator and application thereof 丹娜法伯癌症研究院 2023-12-29 CN disclosed
WO-2019228345-A1 ANTIBODY BINDING TO AXL PROTEIN AND APPLICATION THEREOF 杭州尚健生物技术有限公司 (CN) 2019-12-05 WO disclosed
US-20190136192-A1 MESENCHYMAL STEM CELL THERAPY FOR SPINAL MUSCULAR ATROPHY CELL MEDICINE, INC. (US) 2019-05-09 US disclosed