Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | CALML3 | P27482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290108 | 0.92 | CD274 (0.36) | CD274MAPK13PRMT5WDR77CALML3 | |
| Hydrochloric Acid SCHEMBL1290207 | 0.91 | CD274 (0.36) | CD274MAPK13PRMT5WDR77CALML3 | |
| Potassium Ion SCHEMBL12502276 | 0.88 | CD274 (0.33) | CD274MAPK13PRMT5WDR77 | |
| SCHEMBL5423207 | 0.84 | CD274 (0.35) | CD274MAPK13PRMT5WDR77 | |
| SCHEMBL19712464 | 0.84 | CD274 (0.36) | CD274MAPK13GRM2 | |
| SCHEMBL19723481 | 0.83 | — | — | |
| SCHEMBL5415055 | 0.81 | KDM4C (0.34) | CD274MAPK13 | |
| SCHEMBL15262056 | 0.80 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL15261667 | 0.80 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL1290126 | 0.79 | NOTUM (0.34) | CD274MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476844-A1 | ANTIMICROBIAL 4-OXOQUINOLIZINES | Emergent Product Development Gaithersburg Inc. (US) | 2019-05-01 | — | — | EP | disclosed |