Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 13/20 | 0.68 |
| ▸ | FGFR4 | P22455 | 15/20 | 0.59 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.59 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21019614 | 0.94 | FGFR1 (0.76) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20960536 | 0.91 | FGFR1 (0.56) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20943048 | 0.89 | FGFR1 (0.67) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20943025 | 0.87 | FGFR1 (0.67) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20942967 | 0.86 | FGFR4 (0.65) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20942972 | 0.85 | FGFR4 (0.64) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20943014 | 0.84 | FGFR1 (0.61) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20942975 | 0.83 | FGFR1 (0.54) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL20943060 | 0.83 | FGFR1 (0.58) | FGFR1FGFR4FGFR2FGFR3CYP1A2 | |
| SCHEMBL20943009 | 0.82 | FGFR1 (0.59) | FGFR1FGFR4FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476846-A1 | NOVEL HETEROCYCLIC DERIVATIVE COMPOUND AND USE THEREOF | Hanmi Pharmaceutical Co., Ltd. (KR) | 2019-05-01 | — | — | EP | disclosed |